A collaboration with Ecole Nationale Vétérinaire d’Alfort and INRAE teams led to the publication of this article. We showed that contaminant OTUs from sample laboratory processing steps can represent more than half the total sequence yield in sequencing runs, and lead to unreliable results when characterizing tick microbial communities. We thus strongly advise the routine use of negative controls in tick microbiota studies, and more generally in studies involving low biomass samples. You can access this article here.
Migale Bioinformatics Facility
We provide several services for scientists to deal with life sciences data
Our Services
Migale, one of the Collective Scientific Infrastructure of INRAE, is part of the BioinfOmics Research Infrastructure of INRAE for bioinformatics. It is also a member of IFB (Institut Français de Bioinformatique), the French bioinformatics infrastructure and associated facility of France Génomique, the French genomic infrastructure for which we contribute to support different developments in bioinformatics.
A free account gives you access to work and save directories for your data, and access to the computer farm for your analyses.
The cluster farm is composed of about a thousand cores organized in different queues. We use the Sun Grid Engine queuing system for managing jobs.
You have a free access to our Galaxy server. Galaxy allows non-bioinformaticians to easily run tools without technical knowledges.
Command line tools, R packages and Galaxy wrappers are available on request and accessible to all migale authenticated users.
We provide an access to a large set of public biological databanks including whole genomes, nucleic and proteic sequences and other resources. They are updated automatically with BioMaJ or upon request.
We write tutorials to help you get familiar with tools, best practices, languages, etc.
Each year, we offer our "Bioinformatics by practicing" cycle. This cycle covers a broad spectrum of bioinformatics. The modules mix theoretical part and practical work.
We answer to the most common questions regarding the technical difficulties you can go through on our infrastructure.
Find all the ways to contact us.
New tools installation mode
From now on and as far as possible, we install our tools under the "conda" environment.
This allows us to avoid conflicts between the different dependencies of each tool.
We will gradually remove the "classic" "old" installations to keep only the "conda" versions. Beginning June 19th, all tools will be available only via Conda.
Help on how to use the tools under "conda" can be found here: https://migale.inra.fr/faq#migale-condalist
Effect of COVID-19 outbreak on Migale facility
Due to recent developments in the COVID-19 epidemic, all facility staff is now teleworking. Some of us with children at home. We are commited to keep the platform running and answer to your requests as quickly as possible. Please excuse in advance any delay that may occur.
The facility shutdown initially planned at the end of the month (March 30th) is postponed at an unknown date.